Everyday wear and tear: repetitive and excessive force on a joint may wear down the supporting tissues of the joints
Weight Bearing joints: knee, hock, fetlock, pastern and coffin joints are more prone to be arthritic since they endure the majority of the concussive forces
Poor conformation: may cause abnormal forces, placing additional strain on joints
Other injury: bacterial infection (septic arthritis) and joint fractures will stimulate an inflammatory response